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Approaches for unveiling the kinetic mechanisms of voltage gated ion channels in neurons
(University of Missouri--Columbia, 2019)
Ionic currents drive cellular function within all living cells to perform highly specific tasks. For excitable cells, such as muscle and neurons, voltage-gated ion channels have finely tuned kinetics that allow the ...
The ecological roles of amphibians and subsidies in ponds
(University of Missouri--Columbia, 2018)
Freshwater ponds are often underappreciated landscape features, despite the fact they comprise a major portion of all freshwater ecosystems. Ponds support diverse food webs and species not found in other habitat types. ...
Uncovering the genetic basis of seed amino acid composition in arabidopsis using a multi-omics integrative approach
(University of Missouri--Columbia, 2021)
Seeds are a vital source of protein in the diet of humans and livestock. However, protein composition in the seed is low, comprising about 10 percent of the total composition in the seed. Additionally, protein quality in ...
Neuroscience tools in novel contexts: developing thermogenetics in Drosophila and decoding autonomic activity in mouse major pelvic ganglion
(University of Missouri--Columbia, 2022)
Animal research models provide the opportunity to decode neural activity via the ability to precisely stimulate and record neural events associated with quantifiable circuit and behavioral outputs (Bernstein et al., 2012; ...
The power of synteny : deep evolutionary insights from comparative genomics
(University of Missouri--Columbia, 2021)
Synteny, or the order of genes in a given genome, is an emergent property of individuals and species that has only, with the implementation of next gen-sequencing, become available for evolutionary consideration. In this ...
The genetic and physiological basis of total energy budget in different nutritional environments
(University of Missouri--Columbia, 2020)
Organisms need to adapt to dynamic environments over time. An organism consumes and stores a finite amount of resources that are used for all daily tasks. In order to survive and thrive, they must allocate these finite ...
Celsr1 suppresses WNT5A-mediated chemoattraction to prevent incorrect rostral migration of facial branchiomotor neurons
(University of Missouri--Columbia, 2022)
As the nervous system develops, neurons often migrate from where they originate to their functional locations prior to them contributing to the circuits that drive cognitive and motor function. Within the vertebrate ...
Brassicales to Brassica : integrating phylogenomics and population genomics
(University of Missouri--Columbia, 2020)
The Brassicales are an economically important order of flowering plants. Many crop species such as kale, broccoli, cabbage, cauliflower, canola oil, capers, and papaya, as well as the model plant organism, Arabidopsis ...
Friends in high places : ecology of mycorrhizal associations in alpine plant communities
(University of Missouri--Columbia, 2010)
Mutualisms are ubiquitous in nature, yet these interactions often vary in strength and persistence. This variation raises the questions of what determines whether mutualisms persist or vanish, and how does variation in the ...